Executive Director - Head of Respiratory, Inflammation and Autoimmunity Companion Diagnostic Unit @ Accountable for ensuring that companion diagnostic tests or equivalent segmentation tools are delivered to drug products within the Respiratory, Inflammation and Autoimmunity (RIA) Therapeutic area. From January 2014 to Present (1 year 10 months) Cambridge, UKExecutive Director - Diagnostic Development @ From September 2013 to December 2013 (4 months) Alderley Park, Cheshire, UKDiagnostic Development Team Director @ From July 2011 to September 2013 (2 years 3 months) Alderley Park, Cheshire, UKBiomarker Experimental Medicine Leader @ From September 2008 to June 2011 (2 years 10 months) Welwyn Garden City, Herts, UKSenior Group Leader - Molecular and Cellular Biology @ From January 1999 to July 2008 (9 years 7 months) Cambridge, United KingdomPostdoctoral Research Associate @ Research in the laboratory of Prof. Richard Reece centred on the reconstruction of the Saccharomyces cerevisiae GAL genetic switch in vitro to further our understanding of the molecular mechanisms underlying eukaryotic gene regulation.
Platt, A., Ross, H., Hankin, S. and Reece, R.J. (2000) The insertion of two amino acids into a transcriptional inducer converts it into a galactokinase. PNAS. 97 (7): 3154 – 3159.
Platt, A. and Reece, R.J. (1998) The yeast galactose genetic switch is mediated by formation of a Gal4p/Gal80p/Gal3p complex. EMBO. J. 17 (14): 4086-4091. From July 1995 to December 1998 (3 years 6 months) Postgraduate Research Assistant @ Research within the laboratory of Prof Mark X. Caddick focussed on the Identification and dissection of molecular signal transduction domains within the transcription factor areA.
Platt, A., Langdon, T., Arst, H.N., Kirk, D., Tollervey, D., Mates Sanchez, J.M., and Caddick, M.X. (1996) Nitrogen metabolite repression involves the C-terminus and the GATA domain of the Aspergillus transcription factor AREA and the 3'-untranslated region of its mRNA. EMBO. J. 15 (11): 2791-2801.
Platt, A., Ravagnani, A., Arst, H.N., Kirk, D., Langdon, T., and Caddick, M.X. (1996) Mutational analysis of the C-terminal region of AREA, the transcription factor mediating nitrogen metabolite repression in Aspergillus nidulans. Mol. Gen. Genet. 250 (1): 106-114. From August 1990 to January 1995 (4 years 6 months)
PhD, Molecular Genetics @ University of Liverpool From 1991 to 1995 Professional Certificate in Management @ The Open University From 2004 to 2004 Adam Platt is skilled in: Biomarkers, Clinical Development, Pharmaceutical Industry, Biomarker Discovery, Lifesciences, Biotechnology, Translational Research, Genomics, Biochemistry, Molecular Biology, Personalised Healthcare..., Drug Discovery, Translational Medicine, Drug Development, Pharmacology, Drug Design, Signal Transduction, In Vitro, Genetics, Immunology, Oncology, Assay Development, Life Sciences