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Jonathan Siegrist

VP, Technology & Innovation

VP, Technology & Innovation at Cepheid

Campbell, California

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Jonathan Siegrist's Email Addresses & Phone Numbers

Jonathan Siegrist's Work Experience


VP, Technology & Innovation

Sunnyvale, California


Senior Director, Engineering

March 2017 to September 2018

Sunnyvale, California


Director, Engineering Programs

October 2013 to March 2017

Sunnyvale, CA

Jonathan Siegrist's Education

UC Irvine

Ph.D., Biomedical Engineering

2006 to 2009

UC Irvine

M.S., Biomedical Engineering

2005 to 2006

University of California, Los Angeles

B.S., Electrical Engineering

2000 to 2005

About Jonathan Siegrist's Current Company


About Jonathan Siegrist

đź“– Summary

VP, Technology & Innovation @ Cepheid Sunnyvale, CaliforniaSenior Director, Engineering @ Cepheid -Promoted to Senior Director, Engineering reporting directly to the Cepheid President/CEO as overall program lead for the new GeneXpert Omni system under development-Duties include overseeing the entire Omni program from technical hardware and software (incl. cloud connectivity), marketing, NPI, instrument and consumable manufacturing, verification, validation, and CE-IVD mark / CLIA-Waiver From March 2017 to September 2018 (1 year 7 months) Sunnyvale, CaliforniaDirector, Engineering Programs @ Cepheid • Cepheid’s technical program lead for the Biohazard Detection System (BDS), a national security partnership between Cepheid, United States Postal Service (USPS), and Northrop-Grumman (NG) to screen mail for Anthrax w/molecular testing• Leading all of Cepheid’s technical, business, and customer aspects of the BDS program, including supply of consumable test cartridges to USPS and service/support of system hardware for NG (duties include forecasting, supply chain management, manufacturing management, shipping/transportation logistics, technical change control, contract negotiations, resolution of field issues, database management & monitoring, and regular partner meetings with both USPS & NG)• Successfully addressed several business continuity concerns with the BDS program while maintaining a $20 mil+ yearly revenue stream in a time of rapid change with USPS and mail demand• Established and am leading a new Engineering Consumables R&D group, which has been grown to 4 Engineers/Scientists in support of a strategic Engineering project to enable high-multiplexing PCR in Cepheid’s GeneXpert systems• Engineering R&D work has included research, development, and testing of specific fluidic parts, establishing feasibility for injection molding of these parts as a new consumable cartridge component, and establishing PCR proof-of-concept• Additional Engineering R&D responsibilities have included equipment/infrastructure updates to the R&D labs as well as to Cepheid’s molding/tooling facility, overall project schedule, budget, and deliverables tracking (including regular updates to the Senior Executive team), and cross-functional coordiation to ensure manufacturing, software, hardware, and biological requirements are incorporated• Have coached the individual Consumables R&D team members and developed the overall group to create a high-functioning, productive, and innovative product development team From October 2013 to March 2017 (3 years 6 months) Sunnyvale, CAProject Manager || Research & Development @ Cepheid • Worked as a project manager for Cepheid’s Research and Development groups, including Engineering, Systems Integration, Software, and BioAssay projects• Acted as the sole Systems/Software program/project manager, including projects for developing GeneXpert systems, GeneXpert software, and new consumables/cartridges• Duties included Core Team formation, schedule development and tracking, conflict management, resource management, risk management, and adherence to ISO 13485 from concept to product launch and post-market surveillance• Managed large, cross-functional, international Core Teams while significantly contributing to design, verification/validation, manufacturing, regulatory, and marketing initiatives, among others• Additional duties included strategic program planning at the Executive level and product lifecycle improvements• Successfully launched over 10+ IVD products in under 2 years, including systems projects (Infinity-80 and Infinity-48s instruments, Xpert Calibration), software products (Xpertise and Dx product software), and assays (Xpert CT/NG, Xpert Flu) From July 2011 to October 2013 (2 years 4 months) Sunnyvale, CA, USAPost-Doctoral Biomedical Engineer || Microfluidic Immunoassay R&D @ Biomedical Diagnostics Institute Under Dr. Jens Ducrée• Worked as a post-doctoral researcher in the microfluidics group at the Biomedical Diagnostics Institute in Dublin, Ireland• Research work was focused on development of an automated, microfluidic immunoassay system in collaboration with Millipore, including the integration of microfluidic sample prep, surface chemistry, fluorescence detection, and hardware instruments• Other projects included a magnetics-based bioseparation platform, unique valving methods, and new surface chemistries• Also set up entirely new labs and installed new lab infrastructure, including process development and lab management• Additional tasks involved student mentoring and supervision, including the management of several M.S. and B.S. students From April 2010 to June 2011 (1 year 3 months) Dublin, IrelandCo-Founder & Engineer || Continuous Glucose Monitoring R&D @ iGlyko, Inc. • Worked on the development of an intravenous, fiber-optic glucose sensor for in-hospital tight glycemic control (TGC) using genetically engineered proteins, including co-founding a start-up company (iGlyko, Inc.)• General duties included setting up laboratory space and assisting in creation of research and business teams through training and recruitment• Scientific duties included management of a small team for fiber-optic system design, protein handling chemistries, hydrogel optimization, development of protocols, hardware automation, and detailed development planning• Established in vitro sensitivity & specificity proof-of-concept in whole blood• Business duties included business plan writing/presentations, searching for funding from investors (angels, investment bankers, and VCs), grant writing (SBIRs), and webmaster From July 2006 to June 2011 (5 years) Orange County, California AreaPh.D. Biomedical Researcher || Microfluidic Platforms for Nucleic Acid-Based Disease Diagnostics @ UC Irvine Under Dr. Marc Madou• Research for doctorate degree that involved construction of centrifugal microfluidic sample lysis, PCR, and DNA microarray hybridization platforms to integrate into a sample-to-answer system for rapid, automated infectious disease diagnostics as part of a multi-million dollar, international Genome Québec initiative• Developed a microfluidic system for bacterial detection that combined cell lysis with real-time PCR as part of a DARPA-sponsored initiative within the unique MF3 center• Utilized microfabrication and manufacturing skills to create disposable, low-cost, polymer microfluidic devices both in and out of cleanroom facilities• Fabricated and automated platform instrumentation, including fluorescence detection systems, feedback control systems for thermocycling, and magnetic actuation systems for sample preparation• Research work also included handling and performing relevant biological assays, such as the optimization of qPCR reactions and the handling of blood/cells• Additional duties included lab management, webmaster, and numerous grant writing efforts (NIH, NSF, and others) From January 2006 to December 2009 (4 years) Irvine, CABiomedical Engineering Consultant @ Symbient Product Development • Provided consulting services for several ongoing projects• Work included design concepts and background research for medical devices involving meso/microfluidic components From 2009 to 2009 (less than a year) R&D Biochemist || RNA Amplification Assay Development @ Hologic (formerly Gen-Probe) Under Dr. Norm Nelson• Worked in the Hologic (formerly Gen-Probe) biochemistry R&D group on RNA amplification and detection assays• Developed and optimized various forms of transcription-mediated amplification (TMA) assay for prostate cancer diagnostics• Reactions were run in a 96-well plate format using real-time molecular probes for multiplexed detection• Work included designing and carrying out experiments as well as data analysis and quantitation• Additional tasks involved instrumentation optimization such as protocol development for magnetic bead-based target-capture and automated well-plate dispensing From September 2007 to December 2007 (4 months) San Diego, CAUndergraduate Researcher || MEMS Neural Stimulation Probes and 3D Electrodeposition @ UCLA Under Dr. Jack Judy• Worked in a microsystems (MEMS) lab on micromachined, deep-brain stimulation probes for Parkinson’s Disease research• Tasks included running tests to determine optimum electroplating conditions for micro-probe production, circuit design/construction, and packaging of external circuits for animal testing• Also worked on electroplating simulations involving 3D modeling using MATLAB, and validation of the models for accuracy against experimental, 3D plated structures• Was trained in UCLA's Nanofabrication facilities and well versed in the basic equipment and processes involving the fabrication of devices on Si wafers using oxides, nitrides, polysilicon, and metals in combination with deposition, masking, and etching From October 2001 to March 2005 (3 years 6 months) Los Angeles, CAUndergraduate Research Intern || Biolistics Research @ Lawrence Berkeley National Laboratory Under Dr. Jian Jin• DOE/NSF sponsored undergraduate research fellowship program (ERULF) at the Lawrence Berkeley National Lab• Research involved development of a biolistic gene gun for transfection of C. elegans roundworms• Work included design modifications, experiment design, testing, a research paper, a poster session, and hands on skills such as metal machining, soldering, and programming From June 2002 to August 2002 (3 months) Berkeley, CAUndergraduate Researcher || Quantitative Microscopy Research @ UCSD Under Dr. Jeff Price• Worked in various imaging labs, running phase-contrast image scans of tissue micro-arrays• Was exposed to basics of phase-contrast, fluorescent, confocal, and automated microscopy• Worked on image processing algorithms, specifically Matlab-based, edge-detection software• Was exposed to basics of flow-cytometry From June 2004 to September 2004 (4 months) San Diego, CA

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Frequently Asked Questions about Jonathan Siegrist

What company does Jonathan Siegrist work for?

Jonathan Siegrist works for Cepheid

What is Jonathan Siegrist's role at Cepheid?

Jonathan Siegrist is VP, Technology & Innovation

What is Jonathan Siegrist's personal email address?

Jonathan Siegrist's personal email address is s****[email protected]

What is Jonathan Siegrist's business email address?

Jonathan Siegrist's business email addresses are not available

What is Jonathan Siegrist's Phone Number?

Jonathan Siegrist's phone (213) ***-*208

What industry does Jonathan Siegrist work in?

Jonathan Siegrist works in the Medical Devices industry.

Who are Jonathan Siegrist's colleagues?

Jonathan Siegrist's colleagues are Sepideh Bayat, Tri Tran, Ahmed Madian, Udorn Chanthavong, Jodi Weidler-Houghton, Melissa Le, Sherif Harydi, Cecile Casado, Nicolas Brouchon, and Rachelle MD

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In a nutshell

Jonathan Siegrist's Personality Type

Extraversion (E), Intuition (N), Feeling (F), Judging (J)

Average Tenure

2 year(s), 1 month(s)

Jonathan Siegrist's Willingness to Change Jobs



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