Associate Director, V-Lab @ Students 2 Science, Inc.
Owner @ Depeche Protein
Senior Research Scientist @ Merck
BS, Biology @
University of Michigan-Dearborn
I graduated in 1988 from The University of Michigan – Dearborn with a Bachelors of Science degree in Biology. In 1991, I received my Masters of Science degree in Molecular Biology and Genetics from Wayne State University School of Medicine while studying in the laboratory of Dr. Leon Carlock. In February 1992 I joined Merck Research Laboratories
I graduated in 1988 from The University of Michigan – Dearborn with a Bachelors of Science degree in Biology. In 1991, I received my Masters of Science degree in Molecular Biology and Genetics from Wayne State University School of Medicine while studying in the laboratory of Dr. Leon Carlock. In February 1992 I joined Merck Research Laboratories (Rahway, New Jersey) in the Department of Biophysical Chemistry, as a Staff Chemist working in the laboratory of Dr. Alice Marcy. Through my tenure at Merck & Co., I was promoted three times, worked in eight departments (mostly with the same team) and was involved in over 20 different projects. My products were key drivers of numerous projects that has resulted in co-authorship on over 26 publications. I am a co-Inventor on one patent, was an invited speaker at a national scientific meeting for one of my unpublished projects (FATP5), and have presented posters at 4 national scientific conferences. One of the infectious diseases projects that I contributed to has a compound, MK-7655, currently in Phase III Human clinical trials for the treatment of Gram-negative bacterial infections.
After Research and Development re-organizations in 2011, I was a lab manager, responsible for directing the work of 4 scientists. I was responsible for mentoring 8 summer interns and one UNCF scholar during my employment. I was involved with design, moving and setting up new laboratories on three occasions. I have worked with numerous external collaborators, both academic and commercial, and was responsible for outsourcing of protein and DNA projects. I was responsible for protein production on basic research project teams and managed those efforts independently. Recently, I was a major contributor to successful implementation of our Laboratories 5S (Sort, Set in Order, Shine, Standardize, Sustain) Certification in 2013.
Associate Director, V-Lab @ Our mission to inspire, motivate and educate students to pursue careers in Science, Technology, Engineering, and Math (STEM).
We accomplish this by operating a modern analytical chemistry laboratory for the sole purpose of providing students with a "real life" work experience while introducing them to a wide variety of STEM career opportunities. Middle and high school students visit our laboratory and perform hands-on, age appropriate experiments that emphasize the subjects taught in their classroom and support the State and Federal Core Curriculum standards.
Additionally, S2S provides a supplementary education experience to support teachers in the classroom by way of its Virtual Laboratory (V-Lab) Program. The V-Lab Program consists of a series of supplemental age appropriate, “hands-on” science experiments for grades 4 through 12 to be performed by the students in their local classroom and simultaneously at the S2S Technology Center by use of a fully interactive unified video based communications platform. Technical professionals from the community and local corporations volunteer to work side by side with these young students providing them with support, inspiration and career advice. From July 2015 to Present (6 months) Owner @ Consulting based on my background as a resourceful pre-clinical protein chemist with vast experience in the pharmaceutical industry. Comprehensive knowledge of the drug development process from pre-clinical drug discovery through pre-clinical phase. Impressive track record of working in a cross-functional multi-disciplinary environment and utilizing skills to contribute to project teams to help meet milestones and achievements. Guidance on production of quality protein reagents suitable for a wide-array for Research and Development applications. From November 2013 to Present (2 years 2 months) Senior Research Scientist @ Senior Level Scientist with extensive experience in various research activities of drug discovery including Lead Optimization (LO) and Lead Identification (LID). Worked in diverse disease areas such as cardiovascular and infectious diseases. Trained and supervised research scientists. Familiar with techniques involved in drug discovery including instrumentation and computer related techniques (database mining, alignments). Responsible for planning and summarizing complex technical experiments including analysis, interpretation and evaluation and preparation of appropriate memoranda for distribution. Conducted experiments independently; determined and implied possible solutions for difficult technical problems. Performed scientific literature searches. Recommended and interacted with outside vendors. Understand and comply with Safety, Good Laboratory Practice (GLP), Good Manufacturing Practice (GMP) and Affirmative Action policies and procedures. Familiar with SAP. Proficient in Electronic Notebook usage and compliance.
Senior Scientist:(Band 400) Department of Pharmacology Nov2012 - Nov2013 (KN)
Team Member-Reagent Production:(M06) Department of In Vitro Pharmacology Aug2010 - Nov2012
Team Member-Reagent Production:(M06) Department of In Vitro Sciences May2009 - Jul2010
Research Associate:(M06) Department of Cardiovascular Diseases Feb2009 - Apr2009
Senior Research Associate:(M05) Department of Infectious Diseases Jan2007 - Feb2009
Research Associate:(M06) Department of Infectious Diseases Dec2002 - Dec2006
Research Associate:(M06) Department of High Throughput Screening Nov1999 - Dec2002
Research Chemist:(M07) Department of Molecular Design and Diversity Apr1995 - Nov1999
Staff Chemist:(M08) Department of Biophysical Chemistry Feb1992 - Apr1995 From February 1992 to November 2013 (21 years 10 months) Graduate Student @ Masters of Science Degree (Molecular Biology and Genetics) Advisor: Dr. Leon Carlock. Researching Human Chromosome 4 attempting to discover the gene responsible for causing Huntington's Disease.
Honors: Center for Molecular Biology Graduate Fellowship 1989-1991
Wisniewski,D., 1991. Identification and partial characterization of an unusual tissue-specific gene in the 4p16.3 band of human chromosome 4. From 1989 to 1991 (2 years) Greater Detroit AreaResearch Assistant in the Department of Molecular Biology and Genetics @ Assist the laboratory of Dr. Leon Carlock with stocking reagents. Learn and apply techniques such as: Southern blots, DNA restriction digests, gel electrophoresis, pulse field gel electrophoresis, centrifugation, and PCR. From 1988 to 1989 (1 year) Greater Detroit Area
MS, Molecular Biology and Genetics @ Wayne State University From 1989 to 1991 BS, Biology @ University of Michigan-Dearborn From 1983 to 1988 Dearborn High School From 1980 to 1983 Douglas Wisniewski is skilled in: Protein Chemistry, Molecular Biology, Drug Discovery, Lifesciences, Biotechnology, Cell Biology, Cell, Drug Development, Pharmacology, Immunology, Biochemistry, ELISA, Clinical Development, Cell Culture, Assay Development, Life Sciences, SDS-PAGE, Western Blotting, HPLC
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