VisionGate, Inc.

VisionGate, Inc., is a clinical stage oncology pharmaceutical and diagnostics company with a focus on the early detection and treatment of lung cancer and bronchial dysplasia. The foundation for our diagnostics capability is the proprietary Cell-CT™ 3-Dimensional Cell Imaging and Analysis platform. The Cell-CT platform, using a process called optical computed tomography (CT), produces 3D images of individual cells with the ability to morphologically recognize over 700 structural biomarkers of normal and abnormal cells. The Cell-CT platform can process any liquid biopsy specimen and therefore has potential applicability to detect a wide range of different cancers and cancer biosignatures that could aid in identifying potential treatments using targeted pharmaceutical therapies. Our lead diagnostic product is the LuCED® lung test - a non-invasive sputum-based test that detects abnormal cells which indicate lung cancer and bronchial dysplasia. LuCED lung test utilizes the Cell-CT platform and is in development for the early detection of lung cancer, bronchial dysplasia and the assessment of indeterminate pulmonary nodules (IPN). The LuCED test includes CellGazer™ application, an imaging software tool under development to facilitate cytopathology diagnosis of abnormal cell images detected by the Cell-CT platform. Our lead investigative pharmaceutical product iloprost, an oral prostacyclin analog, has progressed through an NCI-sponsored Phase 2 clinical trial. Iloprost is a potential first-in-class lung cancer prevention drug in clinical development to treat former smokers for the reduction of moderate to severe bronchial dysplasia as measured by the LuCED® lung test. The LuCED test is being developed as a companion diagnostic to iloprost. The LuCED test and iloprost portfolio provides VisionGate the potential unique ability to both identify and treat patients with pre-cancerous bronchial dysplasia. Follow us on Linked In for updates and visit www.visiongate3d.com.