Enara Bio

Enara Bio’s mission is to shine a light on unconventional targets and develop the next generation of cancer immunotherapies designed to treat a broad patient population. Enara Bio is exploring the hidden depths of cancer and T-cell biology to discover and characterize novel immunotherapy targets, such as MR1-presented ligands and Dark Antigens™, which arise from altered cellular processes in cancer cells. We are pioneering approaches to exploit these targets with TCR-directed therapy and other immunotherapeutic modalities. To achieve our mission, we are leveraging our differentiated MR1 ligand complex, Dark Antigen™ and TCR discovery platforms that integrate bioinformatics, immunopeptidomics, metabolomics and immunology in our Oxford, UK-based research lab alongside our extensive immunotherapy development expertise. Enara Bio is backed by leading life science investors, including SV Health Investors, the founding investor, together with RA Capital and Samsara Biocapital. We have a major strategic partnership with Boehringer Ingelheim to discover and validate novel Dark Antigens in up to three tumor types and collaborate with a number of world-class academic institutions, including the Francis Crick Institute, Cardiff University, Johns Hopkins School of Medicine and the University of Oxford, to help drive our differentiated science.