Fifteen years experience at Johnson Space Center in cosmic ray research (measured antimatter) and 4 years in biomedical imaging development. Six years experience in Nuclear Cardiology at The Baylor College of Medicine/Methodist Hospital, Houston where a novel cardiac imaging gamma camera invented by Dr Lacy was extensively evaluated in patients. Founded Proportional Technologies, Inc in 1991. Developed
Fifteen years experience at Johnson Space Center in cosmic ray research (measured antimatter) and 4 years in biomedical imaging development. Six years experience in Nuclear Cardiology at The Baylor College of Medicine/Methodist Hospital, Houston where a novel cardiac imaging gamma camera invented by Dr Lacy was extensively evaluated in patients. Founded Proportional Technologies, Inc in 1991. Developed and evaluated several biomedical imaging instruments including a breast PET imaging system and a pin-hole mouse heart imaging system. Developed and patented two radiopharmaceutical generator systems for human nuclear imaging and sponsored extensive multicenter imaging trials in cardiac and cancer imaging. Over the past 10 years have concentrated on application of proportional wire detectors to homeland security and neutron science applications as an alternative to 3He driven by an extreme shortage caused by cessation of nuclear weapons manufacturing and development. Many successful systems have been tested by the government and commercial methods have been developed for low cost high volume production. See Jeffrey Lacy's Google Scholar Profile for publications.
President @ See Google Scholar Profile at http://scholar.google.com/citations?user=gZRTXekAAAAJ&hl=en
Served as President and Founder of Proportional Technologies, Inc (PTI) since 1991. Accomplishments include. 1) Conceived and put into practice the Boron Coated Straw (BCS) Detector technology for 3He replacement neutron detection. With colleagues at PTI developed manufacturing methods including low cost high volume Boron coating technique facilitating high volume low cost manufacturing. 2) Applied the technology to military, homeland security, and domestic neutron science applications. 3) PTI has delivered over 20 neutron detectors from handheld to portal monitors for successful government testing. 4) Developed a method of gamma ray imaging utilizing thin walled straw detectors having a thin lead wall. Developed arrays of such detectors for 3D PET imaging in small animals and breast cancer patients. 5) Developed a high pressure xenon spectrometer and demonstrated a system delivering 1% energy resolution at 1 MeV. 6) Developed a PET radiopharmaceutical generator system based on Zn-62/Cu-62. Developed kits for use with the generator that achieve synthesis of 3 effective PET imaging agent providing whole body perfusion and hypoxia imaging. 7) Sponsored FDA trials (120 patients) with an effective rest/stress myocardial imaging agent Cu-62 PTSM (MyoPET) receiving an approvable letter from FDA stating “We strongly encourage you to pursue the development of the generator in the preparation of MyoPET for injection.” 8) Developed and conducted animal studies on a method of coronary restenosis treatment using Cu-62 obtained from the Zn-62/Cu-62 generator. 9) Developed a portable multiwire gamma camera and bedside generator, W-178/Ta-178 for human cardiac imaging studies. Obtained an IND for the generator and deployed the system and portable camera at 5 clinical sites. Conducted studies comparing the technique with gamma camera/Tc-99m in over 300 patients. From September 1991 to Present (24 years 3 months) Assistant Professor @ Applied our NASA developed cardiac imaging camera to patient imaging in the Nuclear Cardiology Laboratory and in the Catheterization Laboratory at Methodist Hospital, Houston. Developed IND for production of the Ta178 generator and ultimately began production of the generator on a monthly basis. Produced over 500 patient studies and numerous publications. Developed an intrasurgical cardiac mapping system and applied to cardiac arrhythmia patients leading to a significant spinoff company. development. From September 1985 to September 1991 (6 years 1 month) Research Scientist @ Developed from ground up the multiwire proportional counter capability for a large balloon born magnetic spectrometer. The system consisted of a stack of 50 x 50 cm2 wire detectors having 2 mm wire spacing for use as the means of momentum determination of charged cosmic rays. Developed a unique position readout system that produced a spatial resolution of 1/10 the detector wire spacing by utilization of delay line cathode image charge readout. Participated in the acquisition and analysis of successful flight data that reported for the first time the antiproton and positron fluxes at balloon altitudes and set limits on the existence of antinuclei in the primary cosmic rays. This instrument was the first successful application of magnetic spectrometry applied to space physics. The instrument endurred and was flown in repeated ballooning missions over more than a decade. The latest generation of such instrument "The Alpha Magnetic Spectrometer" was recently installed in the Space Station by commander Mark Kelly during the final misson of Space Shuttle Endeavour.
The final 5 years at NASA were dedicated to application of the multiwire detectors developed for high energy astrophysics to medical imaging. This cullminated in development of a fully functional cardiac imaging system that was employed in patient imaging for many years at Baylor College of Medicine, From September 1970 to September 1985 (15 years 1 month)
PhD, High Energy Physics @ University of Illinois at Urbana-Champaign From 1965 to 1970 Bachelors, Physics @ Oklahoma State University From 1961 to 1965 Jeffrey Lacy is skilled in: Neutron Detectors for Homeland Security, Neutron Detectors for Neutron Science, Straw Radiation Detectors, Neutron Multiplicity and Coincidence Detectors, Well Logging Neutron Detectors, Gamma Ray Spectroscopy, Neutron and Gamma Ray Modeling, MCNP5,6 MCNPX, Bifunctional Radiopharmaceuticals Based on Rapid Cu-62 Chelation, Radiopharmaceutical Kits Cu-62, Cyclotron Production Zn-62, High Resolution Neutron Radiography, Xenon Spectroscopic Detectors, Gaseous VUV Light Detectors, Sensors, Testing
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