I am a proven biologist and product leader who drives new product development, sales and support using scientific knowledge, key opinion leader insight, process improvement and project management. I am passionate about developing new tools and methods to enable customers to solve complex problems in their research and development processes. I am recognized as a team builder and collaborative problem solver who uses positive communications and responsible decision making to lead and influence teams. As such I have managed projects with global partners, including customers and vendor companies, and with internal teams, such as assay service groups and cross-organization product development teams. Most recently I have focused on global product management and project leadership for drug discovery and life science research instrumentation and reagents. I bring this experience along with my strong background as a discovery and development scientist to a product leadership position with a hands-on approach, working directly with customers to understand critical needs and translating these into product and marketing strategies. Key Strengths Include: Drug Discovery & Life Science Assay Tools | Assay Development & Troubleshooting | Cellular Biology | Biochemistry | High Throughput Screening | Molecular Biology | Protein Analysis | Product Management & Project Leadership | Voice of Customer | New Product Development | Critical Thinking | Customer Training and Support Please contact me directly at debra.butts@hotmail.com for contract, consulting and career opportunities.

Global Product Manager - Drug Discovery Systems and Consumables @ Led upstream and downstream global product management of Drug Discovery products, including capital equipment systems, software, and consumables. Product offering responsibility included FLIPR and CellKey systems, and the drug discovery reagent portfolio including FLIPR reagents, with a value of 15% of total company revenue. • Led new reagent development initiative (OpCo top priority project), successfully launching 4 new reagents for drug discovery and life sciences, driving 4 more into development in less than 12 months. Delivered 98% of target revenue for new products and mitigated the overall reagent portfolio revenue decline seen in prior 4 years, growing the business by more than 5%. Project manager for two of the new products launched. • Planned and executed 5 system product launches for capital equipment, software, and consumables. Led product strategy and roadmaps, planned and executed launch campaigns including delivery of all sales tools and training materials and generated continued product awareness and leads. • Influenced and led core teams to bring new products to market. Worked closely with customers, sales and product development to define specifications and prioritize features to ensure new products met customer expectations and needs. • Generated customer-facing marketing and training presentations, posters, application notes, and other sales tools. Authored and delivered presentations/posters at conferences and customer sites. • Established and nurtured collaborative partnerships with key opinion leaders, customers, and vendor companies to expand applications, support new product opportunities, engage beta evaluation programs, and to increase lead generation. Molecular Devices known as MDS Analytical Technologies from 2007-2009 From 2007 to 2014 (7 years) Sunnyvale CAApplication Scientist @ Supported global launch and sales of a novel label-free cellular analysis platform consisting of instrumentation, software, and consumables. • Led collaborations with pharmaceutical and biotech research teams worldwide leading to increased product adoption; including generating/oversight of project charters, performing off-site demos and in-house feasibility studies, and preparing/delivering customer-facing data reports and presentations. • Provided global customer applications support, including troubleshooting issues related to user technical skill, instrument operation, experimental design, and data analysis. • Equipped customers to use products effectively, minimizing service support requirements, by conducting on-site and in-house customer training courses throughout North America and Europe. • Served as customer team lead, delivering voice of customer feedback and prioritizing requirements for in-house development of new applications, products and services. From 2005 to 2007 (2 years) South San Francisco, CAScientist @ Conducted evaluation, development, and production of reagents, assay methods and assay kits for internal and external customers to support cell biology, drug discovery, and diagnostic programs. • Defined and managed collaborations including project charters, success criteria and timelines so as to ensure clear expectations across organizations. Managed customer expectations through frequent and consistent communication on progress and data via data report generation and presentation. • Products developed included (1) Microscopy assay kit for Q-Dot nanocrystal-labeled antibodies including optimized reagents and methods. (2) Homogenous multiplexed FLISA assay with antibody coated polystyrene particles for FMAT 8200 and other macro-confocal imaging systems. (3) Optimized methods for a fluorescence-based translocation/redistribution assay screening GPCR agonists and antagonists via imaging systems. (4) Conjugation of customer antibodies to multiple fluorophores. From 2003 to 2005 (2 years) San Carlos, CAResearch Investigator @ Engaged in early drug discovery research and development of novel therapeutics for oncology, metabolic and inflammatory disease programs. This included assay development, high throughput and lead optimization screening, pharmacology, new technology evaluation (detection and automation systems), and small molecule characterization. Excellence in achieving objectives was recognized by three promotions in five years. Kinase Programs ► Dual-role as project leader and hands-on scientist tasked with developing and running a high-throughput kinase selectivity screening platform, to characterize potency and selectivity activity, in support of lead discovery and lead optimization efforts for internal and alliance kinase programs. Integrin and Chemokine Programs ► Continued work on programs from LeukoSite, Inc position. (LeukoSite acquired by Millennium in Dec 1999) From 2000 to 2004 (4 years) Cambridge, MAResearch Associate @ (LeukoSite acquired by Millennium Pharmaceuticals in Dec 1999) Engaged in drug discovery research and development of novel therapeutics for inflammatory disease programs. Targets included GPCRs and Integrins. Involved in all aspects of early drug discovery including assay development for medium and high throughput screening, HTS and lead optimization screening, new technology evaluations, small molecule characterization, protein production and purification, and receptor mutagenesis studies. ► Developed and performed numerous in vitro assays including adhesion assays, flow cytometry, radioligand binding assays, for HTS and lead optimization of small molecular weight compounds and peptides. ► Evaluated and developed Ligand Binding Assays for integrin and chemokine targets utilizing FMAT 8100, FACScan and FACSCalibur, TRF and other technologies for detection. ► Participated in the set up of companies’ first robotics-based high throughput screening lab and adapted low-to-medium throughput assays to high-throughput. ► Produced, purified, and characterized proteins and conjugates for program assay reagents. Performed ELISA, protein gel analysis, Western Blot and immunoprecipitation techniques for characterizations. ► Maintained and ensured QC of a large number of cell lines necessary for program support. From 1996 to 2000 (4 years) Cambridge, MAResearch Assistant I @ Center for Gastroenterology Research on Absorptive and Secretory Processes (GRASP) Studied physical and behavioral changes of Cholecystokinin A and B knock-out mouse populations as a member of a research group devoted to the study of normal and abnormal gastroenterology absorptive and secretory processes. Performed general molecular biology techniques for genotype identification and developmental studies, such as Southern and Northern blot analysis. Responsible for colony oversight and husbandry. From 1995 to 1996 (1 year) Boston, MAResearch Associate @ Performed small molecular weight drug testing, assay development, cell and antibody screening assays and cell culture in support of the development of novel cancer therapeutics. Developed new assays for testing toxicity, concentration and quality of immunoconjugates and individual components. Utilized FACScan technology to evaluate binding of antigens and modified antibody samples to cell lines. From 1994 to 1995 (1 year)

BA, Biology @ Mount Holyoke College From 1990 to 1994 Debra Butts is skilled in: Assay Development, Drug Discovery, Lifesciences, Immunoassays, Cell, Biotechnology, Laboratory Automation, Cell Biology, Genomics, Cell Culture, PCR, Molecular Biology, DNA sequencing, Biochemistry, Commercialization, Project Management, Robotics / Assay..., Life Sciences, R&D, High Throughput..., In Vitro