Qing-Fen Gan's Email

Self-motivated and innovative scientist with extensive experience in pharmaceutical industry as both a bench scientist and a group head in Roche’s Discovery Technologies (DT) department. In-depth knowledge and expertise in biochemical and cell-based assay development, screening/automation technologies, and data analysis/QC. Extensive supervisory experience in managing PhD, MS and BS scientists. A proven team player with good communication skills.

Associate Director, Head of Discovery Biology @ From April 2013 to Present (2 years 9 months) Senior Principal Scientist @ •Lead an assay development/automation group to support lead discovery projects in Inflammation and Virology disease areas. -Design and implement assay/screening strategies, including developing and validating biochemical and cell-based screening assays, reagent characterization, compound profiling, and inhibition mechanism studies. -Lead group to conduct primary HTS, follow up screens and support lead optimization process. -Conduct data quality control and analysis using multiple IT/informatic tools. •Collaborate with scientists from cross-functional teams in different disease areas to provide expert advice in assay design, validation, and quality assessment. •Interact with CRO companies to manage outsourced projects. •Invent, evaluate, and introduce new assay technologies to in-house drug development process. •Member of Roche’s global New Assay Technology Workgroup charged with identifying and evaluating new assay approaches and instruments, and making investment recommendations to global DT Management Team. From September 2009 to April 2013 (3 years 8 months) Principal Research Scientist @ •Design, and implement assay/screening strategies, including developing and validating biochemical and cell-based screening assays, reagent characterization, compound profiling, and inhibition mechanism studies on many different target families to support Inflammation, Virology and CNS disease areas. •Conduct primary HTS, follow up screens and support lead optimization processes. •Data analysis and data QC. •Interact with scientists in different disease areas to provide expert advice in assay design, validation, and quality assessment. •Prepare and lead “Active Compound Review” meetings using PipelinePilot, Spotfire, Microsoft Access and other IT tools to support initial SAR studies. •Invent, evaluate, and introduce new assay technologies to in-house drug development process. •Member of Roche’s global New Assay Technology Workgroup charged with identifying and evaluating new assay approaches and instruments, and making investment recommendations to global DT Management Team. From July 2003 to September 2009 (6 years 3 months) Research Scientist II @ From January 1999 to June 2002 (3 years 6 months) Research Scientist I @ From January 1997 to January 1999 (2 years 1 month) Post doctor fellow @ From 1993 to 1997 (4 years)

Ph. D., Biochemistry @ Johns Hopkins UniversityB.S., Chemistry @ Peking University Qing-Fen Gan is skilled in: Biochemical and cell-based assay development, Lab automation, Data Analysis, Compound clustering, HTS data quality control, label-free technologies, Lead identification and optimization, Microsoft Excel, Access, Genedata, Spotfire, Protein Chemistry, Project Management, CRO outsourcing management, Assay Development, Inflammation, Spotfire