Petra LeBeau's Email Addresses & Phone Numbers

📖 Summary

Visiting Fellow / Post-doctoral Student @ National Institute of Environmental Health Sciences (NIEHS) • Studied the impact of air pollution and temperature on human health (cardiovascular and respiratory outcomes).• Developed and implemented physiologically-based pharmacokinetic (PBPK) models.• Re-evaluated the EPA’s assessment of cancer susceptibility from early-life exposure to carcinogens.• Methodologies used: GLM, GAM, GEE, non-linear models, ODE’s, maximum likelihood estimation. From August 1999 to November 2004 (5 years 4 months) Research Assistant in Statistics @ MEMIC; Maastrichtuniversity • Acted as a consultant of methodology and data processing for biomedical research conducted at the Department of Internal Medicine and the Department of General Practice, both at the Academic Hospital in Maastricht, the Netherlands.• Methodologies used: linear and logistic regression, survival analysis, sample size calculations.• Gave presentations of statistical concepts during physician meet-ups. From 1998 to 1999 (1 year) Maastricht, the NetherlandsAssistant Trainer Statistics @ Maastricht University • Assisted in both the planning and teaching of computer laboratory classes in Statistics for students of the Health Sciences department.• Wrote the exercises and solutions syllabi. From 1998 to 1999 (1 year) Maastricht, the NetherlandsPrincipal Biostatistician I @ Rho Durham, North Carolina, United StatesSenior Biostatistician III @ Rho • Functions as project lead on multiple federally funded studies that are mechanistic in nature and produce large data sets (e.g. metagenomics, transcriptomics, epitomes, and wearable devices).• Supervises, organizes and evaluates a team of biostatisticians and provides statistical guidance to the team members and clients.• Independently researches and applies cutting-edge statistical methodologies (e.g. longitudinal and sparse functional data analysis (FDA), trajectory analyses, integrated analysis (systems biology), diagnostic and prognostic modeling including machine learning, machine learning interpretation, network modeling).• Assists in the preparation of proposals and manuscripts.• Subject Matter Expert (SME) for omics type data analyses.• Continues to perform duties of Senior Biostatistician. From April 2016 to February 2020 (3 years 11 months) Research Triangle Park, North CarolinaSenior Biostatistician @ Rho • Served as the lead statistician on multiple federally and commercially funded multi- and single-center Phase I-III studies. Performed project management tasks such as assessing resourcing needs, and updating the scope of work as needed.• Created and reviewed study documents such as Statistical Analysis Plan, Statistical Validation Plan, Randomization Plan, Blinding Plan as well as designed and reviewed display specifications.• Offered statistical guidance to clients and team members on all aspects of project planning and implementation, including trial design, protocol and CRF development.• Designed summary tables, listing and figure specifications for proposed research protocols.• Planned and specified the structure of analysis data sets.• Programmed and validated analysis data sets and display output.• Performed QC on derived datasets and both simple and advanced tables, figures and data listings as well as written text. • Conducted planned and exploratory statistical analyses and interpreted the results using written, oral, and graphical methods, as appropriate for the audience.• Performed a wide variety of statistical activities including: various sample size calculations, randomizations schemes, linear, logistic and Poisson regression analyses.• Prepared statistical reports and displays for client projects, for presentations at meetings or conferences, and for publication in regulatory documents or professional journals.• Developed new statistical methods or applications under the guidance of a more senior biostatistician.• Assisted in the preparation of proposals and budgets as well as attended bid defense meetings on behalf of Rho, Inc.• Attended and/or presented at meetings and conferences.• Served as contact person with other departments.• Supervised and mentored junior and senior level employees.• Interviewed potential new employees and advised in hiring decisions. From January 2006 to March 2016 (10 years 3 months) Biostatistician @ Rho • Study statistician for the NIH-funded Comprehensive Sickle Cell Centers (CSCC) clinical research network.• Contributed to protocol development, performed power and sample size calculations, generated randomization schedules, reviewed case-report forms and participated in the development of both electronic data capture (EDC) and lab tracking systems for Phase II and III clinical trials.• Provided statistical support for ongoing Phase II and III clinical trials.• Learned about the scientific basis of the study and how the data were generated.• Prepared and presented bi-annual DSMB reports, conducted interim analyses of Phase II and III studies.• Prepared statistical analysis plans, statistical reports, interim reports, collaborated with trial investigators to disseminate results. From January 2005 to January 2006 (1 year 1 month) Chapel Hill, North Carolina