Research Associate I, II & Sr. Research Associate I @ Abbott
Research Technician @ BASF
Education:
Bachelor of Science (BS) @
Becker College
About:
Scientist II (In-vivo) @ AbbVie split from Abbott on January 1, 2013,Employment and position are unchanged
• Currently conducting:rat/mouse medial meniscus tear models to support osteoarthritis projects; rat adjuvant and collagen induced arthritis models to support rheumatoid arthritis; as well as developing and executing rat/mouse DSS (Dextran Sulfate Sodium) chemically induced colitis model for GI projects. Major
Scientist II (In-vivo) @ AbbVie split from Abbott on January 1, 2013,Employment and position are unchanged
• Currently conducting:rat/mouse medial meniscus tear models to support osteoarthritis projects; rat adjuvant and collagen induced arthritis models to support rheumatoid arthritis; as well as developing and executing rat/mouse DSS (Dextran Sulfate Sodium) chemically induced colitis model for GI projects. Major contributions to arthritis, osteoarthritis and gastrointestinal initiatives.
• Experience with many in vivo techniques in rodents including: handling and restraint; anesthesia; dosing (IV, IP, SC, ID and PO); peritoneal lavage; blood collection (cardiac puncture, tail nick, vena cava and orbital sinus puncture); surgery (mouse destabilization medial meniscus model, rat medial meniscal tear model, mouse ACL tear model, neonatal cardiac transplantation model, skin transplantation model, rat heterotopic transplantation model, osmotic pump implantation); and necropsy
• Extensive experience with developing, optimizing and executing numerous in vivo disease models: rat collagen induced arthritis; rat adjuvant induced arthritis; rat streptococcal cell wall-induced arthritis; mouse experimental autoimmune encephalomyelitis; mouse destabilization medial meniscus; rat medial meniscal tear; mouse ACL tear; neonatal cardiac transplantation; skin transplantation; rat heterotopic transplantation; mouse and rat DSS induced colitis model; and anti-CD40 induced colitis model in mice
• Skilled in developing and executing numerous acute in vivo models including: zymosan peritonitis model; acute LPS-induced cytokines; acute anti-CD3 induced cytokines; acute concanavalin A induced cytokines; air-pouch model; carregeenan foot pad swelling model; delayed type hypersensitivity (DTH) model; oxazalone contact hypersensitivity; and keyhole limpet hemocyanin (KLH) model
• Conduct various assays to examine pharmacodynamics readouts for disease models and explore biomarkers important to clinical research From January 2013 to Present (3 years)
Master of Science (MS), Biotechnology @ Worcester State University From 2000 to 2003 Bachelor of Science (BS), Veterinary Sciences/Veterinary Clinical Sciences, General @ Becker College From 1993 to 1998
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